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Consider spacing out the applications or reducing the frequency of Tretinoin use if irritation develops

Severe toxicity Toxicity Dosage Calculation manifests as fulminant liver failure Liver failure Severe inability of the liver to perform its normal metabolic functions, as evidenced by severe jaundice and abnormal serum levels of ammonia

2021;9:687598 PMID: 34222255 PMCID: PMC8247587 07/06/2021 (Herrera NA, Duchatsch F, Kahlke A, Amaral SL, Vasquez-Vivar J.) Free Radic Biol Med

Selenium For the thyroid to do its job, the less biologically active T4 needs to be converted to the biologically active T3 hormone

Consider practicing stress-reduction techniques such as meditation, yoga, or deep-breathing exercises